Influence of hydrocarbons on the virulence and antibiotic sensitivity associated with Pseudomonas aeruginosa
| Autor: | Charles P. Gerba, Seema Asthana, Patricia A. Rusin |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
biology
Pseudomonas aeruginosa medicine.drug_class Health Toxicology and Mutagenesis Antibiotic sensitivity Antibiotics Public Health Environmental and Occupational Health Virulence General Medicine medicine.disease_cause biology.organism_classification Pollution Microbiology Bioremediation Antibiotic resistance medicine Organism Bacteria |
| Zdroj: | International Journal of Environmental Health Research. 7:277-288 |
| ISSN: | 1369-1619 0960-3123 |
| Popis: | The bacterium, Pseudomonas aeruginosa has the potential for use in bioremediation. However, this organism is an opportunistic pathogen and is highly resistant to disinfectants and antibiotics. P. aeruginosa has been known to cause a wide variety of infections in humans, especially in immunocompromised persons. The purpose of this study was to assess the influence of hydrocarbons on the virulence of P. aeruginosa as it degrades these hydrocarbons. The expression of virulence factors associated with 12 different hydrocarbon-degrading strains of P. aeruginosa was evaluated. Virulence factors including hemolytic activity, antibiotic sensitivity, cell adherence, and exopolysaccharide capsule formation were tested in the presence of 0.1% glucose and the appropriate hydrocarbon. No differences were found in hemolytic activity or antibiotic resistance in the presence of glucose or hydrocarbon. Growth on glucose significantly enhanced adherence, while growth on a hydrocarbon enhanced capsule formation. The results... |
| Databáze: | OpenAIRE |
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