Chemical and antiplatelet aggregative investigation of the leaves of Clausena excavata
| Autor: | Lai Jeng-Shiow, Ko Feng-Nien, Wu Tian-Shung, Huang Shiow-Chyn, Teng Che-Ming, Kuoh Chang-Sheng |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
chemistry.chemical_classification
biology Stereochemistry Alkaloid Glycoside Plant Science General Medicine Clausena excavata Horticulture biology.organism_classification Coumarin Biochemistry chemistry.chemical_compound Rutin Safrole chemistry Glucoside Scopoletin Organic chemistry Molecular Biology |
| Zdroj: | Phytochemistry. 32:449-451 |
| ISSN: | 0031-9422 |
| DOI: | 10.1016/s0031-9422(00)95013-1 |
| Popis: | A new carbazole alkaloid, clausine-L together with 11 known compounds, safrole, glutinol, 132-hydroxy(132-R)-pheophytin-a, methyl pheophobide-a, scopoletin, steroidal glycoside [β-sitosteryl glucoside +stigmasteryl glucoside], 2-methoxy-4-(2-propenyl)phenyl-β-d-glucoside, 2,6-dimethoxy-4-(2-propenyl)phenyl-β-d-glucoside, p-hydroxybenzoic acid, rutin and nicotiflorin were isolated and characterized from the leaves of Clausena excavata. Their structures were elucidated by spectroscopic methods and/or chemical transformation. Among them, safrole showed significant antiplatelet aggregative activity which was induced by arachidonic acid and collagen. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|