Acute Success of Balloon Aortic Valvuloplasty in the Current Era
| Autor: | Kevin F. Kennedy, Natalie Jayaram, Aimee K. Armstrong, Jeffrey D. Zampi, Brian A. Boe, Diego Porras, Susan R. Foerster |
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| Rok vydání: | 2017 |
| Předmět: |
Aortic valve
medicine.medical_specialty Multivariate analysis business.industry medicine.medical_treatment 030204 cardiovascular system & hematology Logistic regression Balloon medicine.disease Aortic valvuloplasty 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Internal medicine Aortic valve stenosis medicine Cardiology 030212 general & internal medicine Cardiology and Cardiovascular Medicine business Adverse effect Chi-squared distribution |
| Zdroj: | JACC: Cardiovascular Interventions. 10:1717-1726 |
| ISSN: | 1936-8798 |
| DOI: | 10.1016/j.jcin.2017.08.001 |
| Popis: | Objectives The aim of this study was to evaluate practice patterns and outcomes of a contemporary group of patients undergoing balloon aortic valvuloplasty (BAV) for congenital aortic stenosis (AS). Background BAV is the most common treatment for isolated congenital AS. Methods Within the IMPACT (Improving Pediatric and Adult Congenital Treatments) Registry, all BAV procedures performed between January 2011 and March 2015 were identified. Procedures were separated into those performed for critical versus noncritical AS. Outcomes were stratified into optimal, adequate, and inadequate, with optimal and adequate outcomes defining “successful” procedures. Multivariate logistic regression was used to identify patient and procedural characteristics associated with unsuccessful BAV. Mortality and adverse events rates were compared across patient cohorts. Results Of the 1,026 isolated BAV procedures captured in IMPACT, 718 (70%) were “successful.” Success rates were 70.9% for noncritical AS (n = 916) and 62.7% for critical AS (n = 110). Multivariate analysis revealed that prior cardiac catheterization, mixed valve disease, baseline aortic valve gradient >60 mm Hg, baseline aortic insufficiency greater than mild, presence of a trainee, and multiple balloon inflations were associated with unsuccessful BAV in the noncritical AS cohort. There were no factors associated with unsuccessful procedures in the critical AS group. No procedural deaths occurred, but 2.4% of patients did not survive to hospital discharge. Adverse events occurred in 15.8% of all cases and were more frequent in procedures performed for critical AS (30.0% vs. 14.1%; p Conclusions BAV is an effective treatment for congenital AS with low rates of mortality and adverse events. Patients with critical AS have a higher risk for procedure-related adverse events. |
| Databáze: | OpenAIRE |
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