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Background: Pain control through the truncal block of the inferior alveolar nerve is one of the locoregional anesthetic techniques most widely used in oral surgery, affording comfort and safety for both the patient and operator when used correctly. Aim: To compare the anesthetic efficacy of both 4% articaine and 2% lignocaine with epinephrine in the truncal block of the inferior alveolar nerve during surgical removal of the impacted mandibular third molars. Materials and Methods: A randomized, double-blind, clinical trial was conducted of 360 patients programmed for the surgical extraction of symmetrical lower third molars in the context of the Master of Oral Surgery and Implantology (Saveetha Dental College, Saveetha University, Chennai, India). Following the obtainment of informed consent, two operators performedsurgery on an extemporaneous basis, using as local anesthetic 4% articaine or 2% lignocaine, with the same concentration of a vasoconstrictor (epinephrine 1:100,000). The study variables for each anesthetic were: Latency (time to action) and duration of anesthetic effect, the need of reanesthetizing the surgical zone, and intraoperative pain intensity measured objectively using the Visual Analog Scale (VAS) and Faces Pain Scale (FPS). Data were analyzed using the Independent t -test and Chi-square test. Results: A statistically significant difference ( P P Conclusion: We conclude that 4% articaine has better anesthetic efficacy as compared to 2% lignocaine. This can be explained based on its different chemical structure, liposolubility, increased protein-binding ability, diffusion in soft tissue, and increased pulpal anesthesia. |
