Chemistry of indoles carrying basic functions. I. Transformation of hydroxyindolones into indoles
| Autor: | Eszter Gács-Baitz, István Moldvai, Csaba Szántay |
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| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Recueil des Travaux Chimiques des Pays-Bas. 110:437-440 |
| ISSN: | 0165-0513 |
| Popis: | 3-Hydroxy-3-[(2- and 4-pyridyl)methyl]-1H-indol-2-ones (1, 12) have been reduced with NaBH4/MeOH/t-BuOH. After acidic treatment, 2- and 3-substituted indoles (2, 11 and 13, 14, respectively) were obtained. The intermediates 3 and 4 of the rearrangement were isolated and the effect of the pyridylmethyl groups on the rearrangement has also been established. |
| Databáze: | OpenAIRE |
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