A Study of the Electrophilic Aroylation of 1-Aryl-1H-pyrroles: An Improved Preparation of an Active and Selective Aldose Reductase Inhibitor

Autor:	Vassilis J. Demopoulos, Panagiota Kotsampasakou, Nikolaos Sakalis, Nikolaos Kontonikas
Rok vydání:	2019
Předmět:	010405 organic chemistry Stereochemistry Aryl Organic Chemistry Biological activity 010402 general chemistry 01 natural sciences Aldose reductase inhibitor 0104 chemical sciences chemistry.chemical_compound chemistry Electrophile medicine Moiety medicine.drug
Zdroj:	Organic Preparations and Procedures International. 51:147-152
ISSN:	1945-5453 0030-4948
DOI:	10.1080/00304948.2019.1577109
Popis:	The aroyl-1-aryl-1H-pyrrole moiety is an important scaffold present in a number of biologically active compounds.1–5 Based on such precedent, we were prompted to study the electrophilic benzoylatio...
Databáze:	OpenAIRE
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