Pre-clinical Microbiology—Atypical Organisms
| Autor: | Cécile M. Bébéar |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Mycoplasma pneumoniae
Minimum bactericidal concentration Mycoplasma biochemical phenomena metabolism and nutrition Biology bacterial infections and mycoses medicine.disease_cause Microbiology Clinical microbiology Moxifloxacin Mic values medicine heterocyclic compounds Chlamydia trachomatis Ureaplasma urealyticum medicine.drug |
| Zdroj: | First International Moxifloxacin Symposium ISBN: 9783642640810 |
| Popis: | The in-vitro activity of moxifloxacin was reviewed and compared to other fluoroquinolones, macrolides, and tetracyclines against atypical and intracellular organisms such asMycoplasma, ChlamydiaandLegionella spp. Moxifloxacin at 0.25 µg/mL inhibited 100% of all the mycoplasma strains tested. AllChlamydia pneumoniae strains were inhibited between 0.06 and 1 µg/mL. Moxifloxacin was very effective againstLegionella pneumophilawith a MIC of 0.06 µg/mL. The MBC values of moxifloxacin againstMycoplasma pneumoniaeandChlamydia pneumoniaewere equal to or within one dilution step of the MIC values. Moxifloxacin was effective in eliminatingM. pneumoniaeandC. pneumoniaefrom the lungs of animal models. |
| Databáze: | OpenAIRE |
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