A New Pterocarpan from Erythrina fusca
| Autor: | Chikara Ichino, Hiroaki Kiyohara, Pranorm Khaomek, Nongluksna Sriubolmas, Nijsiri Ruangrungsi, Haruki Yamada, Ekarin Saifah |
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| Rok vydání: | 2004 |
| Předmět: |
Pharmacology
biology Stereochemistry medicine.drug_class Organic Chemistry Pterocarpan Bacillus subtilis biology.organism_classification medicine.disease_cause Antimycobacterial In vitro Enterococcus faecalis Analytical Chemistry chemistry.chemical_compound chemistry Staphylococcus aureus medicine Liquiritigenin Erythrina fusca |
| Zdroj: | HETEROCYCLES. 63:879 |
| ISSN: | 0385-5414 |
| DOI: | 10.3987/com-03-9994 |
| Popis: | A new pterocarpan, 3-hydroxy-10-(3-hydroxy-3-methylbutyl)-9- methoxypterocarpan (1), together with seven known compounds, sandwicensin (2), erythrisenegalone (3), citflavanone (4), liquiritigenin (5), lonchocarpol A (6), lupinifolin (7) and 8-prenyldaidzein (8), were isolated from the stem bark of Erythrina fusca. The structure of 1 was determined on the basis of spectroscopic analyses. Among these compounds, lonchocarpol A (6) exhibited strongly antibacterial activities in vitro against Staphylococcus aureus, Bacillus subtilis and Enterococcus faecalis. Compounds (2, 3, 6 and 7) exhibited weakly antimycobacterial activity with minimum concentrations (MICs) of 100, 50, 50 and 25 µg/mL, respectively. |
| Databáze: | OpenAIRE |
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