Assessment of lower urinary tract function in children with Down syndrome
| Autor: | Hiroyuki Moriuchi, Hiroshi Kanetake, Ichiro Kunitsugu, Kenichi Mori, Mitsuru Noguchi, Shohei Tohbu, Tatsuro Kondoh, Teppei Hatada, Manabu Matsuo, Atsuko Kitamura |
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| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Down syndrome Pediatrics business.industry media_common.quotation_subject Urinary system Case-control study Urination disorder Staccato Urinary incontinence medicine.disease Urination Gastroenterology Lower urinary tract symptoms Internal medicine Pediatrics Perinatology and Child Health medicine medicine.symptom business media_common |
| Zdroj: | Pediatrics International. 56:902-908 |
| ISSN: | 1328-8067 |
| Popis: | Background Despite the fact that functional lower urinary tract symptoms are common among people with Down syndrome (DS), their voiding function has not been studied precisely. Our goal was to assess the lower urinary tract functions in DS. Methods Fifty-five DS children aged 5–15 years old and 35 age-matched control children were evaluated by ultrasonography and uroflowmetry. Results Eleven (20%) DS children had no uresiesthesia, 21 (38%) were urinated under guidance, nine (16%) urinated fewer than three times a day, two (4%) urinated more than 10 times a day, three (5%) used diapers, and 26 (47%) had urinary incontinence. Seven (13%), 15 (27%), and 10 (18%) DS children had weak, prolonged and intermittent urination, respectively, and seven (13%) had urination with straining. In contrast, none of the control subjects had urinary problems. In the uroflowmetrical analysis, 10 (18%), 20 (37%), 11 (20%) and five (9%) DS children showed “bell-shaped,” “plateau,” “staccato” and “interrupted” patterns, respectively; the remaining nine (16%) could not be analyzed. In contrast, 21 (60%), one (3%), four (11%), three (9%) and two (6%) control subjects showed bell-shaped, tower-shaped, plateau, staccato and interrupted patterns, respectively; the remaining four (11%) could not be analyzed. Residual urine was demonstrated in four (7%) DS children and one (3%) control child. Conclusions Lower urinary tract symptoms and abnormal uroflowmetry findings, which can lead to further progressive renal and urinary disorders, are common in DS children. Therefore, lower urinary tract functions should be assessed at the life-long regular medical check-ups for subjects with DS. |
| Databáze: | OpenAIRE |
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