Effects of glucomannan supplementation on weight loss in overweight and obese adults: A systematic review and meta-analysis of randomized controlled trials
| Autor: | Kurosh Djafarian, Aliyu Jibril Tijani, Parivash Ghorbaninejad, Sakineh Shab-Bidar, Saba Mohammadpour, Mohammad Reza Amini, Hossein Shahinfar, Mahshid Shahavandi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Endocrinology Diabetes and Metabolism MEDLINE Glucomannan 030209 endocrinology & metabolism Overweight law.invention 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Randomized controlled trial Weight loss law Internal medicine Internal Medicine medicine 030109 nutrition & dietetics business.industry Public Health Environmental and Occupational Health Clinical trial chemistry Sample size determination Meta-analysis medicine.symptom business |
| Zdroj: | Obesity Medicine. 19:100276 |
| ISSN: | 2451-8476 |
| DOI: | 10.1016/j.obmed.2020.100276 |
| Popis: | Objective There are conflicting reports about the effect of glucomannan in the weight control which may be due to the variations in the intervention dose, participants, sample sizes, study durations and overall methodological quality. The present systematic review and meta-analysis were conducted to investigate the effects of glucomannan on weight loss in overweight and obese adults. Methods Relevant studies, published up to April 2020, were searched through PubMed/Medline, Scopus. All randomized clinical trials investigating the effect of glucomannan supplementation on weight loss were included. Results Out of 134 citations, 6 trials that enrolled 225 subjects were included. glucomannan resulted in significant reduction in weight (Weighted mean differences (WMD): −0.96 kg; 95% CI: −1.81 to −0.11, P = 0.02) (I2 = 88.1%, P Conclusion In this meta-analysis we found a significant reduction in body weight following glucomannan consumption in overweight and obese adults. Therefore, the recommendation on glucomannan supplementation could be a practical approach to reduce body weight in overweight and obese adults. Further clinical trials assessing the effect of glucomannan on body composition are needed and a validated methodology for measuring that should be used. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect