Refractory hyperkalaemia associated with trimethoprim-sulfamethoxazole therapy in neutropaenic sepsis

Autor: Manoj Edirisooriya Maddumage, Atapattuge Yamini Anuchana Gunasekara, Waruni Rangika Samaranayake
Rok vydání: 2017
Předmět:
Zdroj: Sri Lankan Journal of Anaesthesiology. 25:122
ISSN: 2279-1965
1391-8834
DOI: 10.4038/slja.v25i2.8250
Popis: Hyperkalaemia is a potentially life threatening electrolyte disorder commonly seen in critically ill patients secondary to renal impairment. Herein, we report a case of severe hyperkalaemia, which was disproportionate to the degree of renal impairment, associated with neutropaenic sepsis, in a critically ill middle aged gentleman. Hyperkalaemia was refractory to medical treatment necessitating haemodialysis in the background of recent administration of trimethoprim- sulfamethoxazole (TMX-SMX) for presumed pneumocystis jiroveci pneumonia. It is important for clinicians to be aware of this complication as TMX-SMX is a popular antibiotic in immunocompromised populations.
Databáze: OpenAIRE