Refractory hyperkalaemia associated with trimethoprim-sulfamethoxazole therapy in neutropaenic sepsis
Autor: | Manoj Edirisooriya Maddumage, Atapattuge Yamini Anuchana Gunasekara, Waruni Rangika Samaranayake |
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Rok vydání: | 2017 |
Předmět: |
Pneumocystis jiroveci pneumonia
medicine.medical_specialty medicine.drug_class business.industry Sulfamethoxazole Antibiotics urologic and male genital diseases medicine.disease Trimethoprim Sepsis Anesthesiology and Pain Medicine Refractory medicine business Intensive care medicine Complication medicine.drug Electrolyte Disorder |
Zdroj: | Sri Lankan Journal of Anaesthesiology. 25:122 |
ISSN: | 2279-1965 1391-8834 |
DOI: | 10.4038/slja.v25i2.8250 |
Popis: | Hyperkalaemia is a potentially life threatening electrolyte disorder commonly seen in critically ill patients secondary to renal impairment. Herein, we report a case of severe hyperkalaemia, which was disproportionate to the degree of renal impairment, associated with neutropaenic sepsis, in a critically ill middle aged gentleman. Hyperkalaemia was refractory to medical treatment necessitating haemodialysis in the background of recent administration of trimethoprim- sulfamethoxazole (TMX-SMX) for presumed pneumocystis jiroveci pneumonia. It is important for clinicians to be aware of this complication as TMX-SMX is a popular antibiotic in immunocompromised populations. |
Databáze: | OpenAIRE |
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