Chemoenzymatic synthesis of analogues of the second messenger candidate cyclic adenosine 5′-diphosphate ribose

Autor:	Antony Galione, Gloria A. Ashamu, Barry V. L. Potter
Rok vydání:	1995
Předmět:	chemistry.chemical_classification Stereochemistry Nicotinamide adenine dinucleotide Adenosine Cyclase chemistry.chemical_compound chemistry Biochemistry Ribose Second messenger system medicine Molecular Medicine Nucleotide Gene Adenosine 5 diphosphate medicine.drug
Zdroj:	J. Chem. Soc., Chem. Commun.. :1359-1360
ISSN:	0022-4936
DOI:	10.1039/c39950001359
Popis:	A broad substrate specificity for adenosine 5′-diphosphate ribosyl cyclase is demonstrated by cyclisation of ribose-and purine-modified nicotinamide adenine dinucleotide analogues to mimics of cyclic adenosine 5′-diphosphate ribose, generating a straightforward route for structural modification of this important Ca2+-mobilising nucleotide.
Databáze:	OpenAIRE
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