Does the Nerve Action Potential Involve a Localized Phase Transition of the Lipid Bilayer?
| Autor: | R M J Cotterill |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Phase transition
Action potential Chemistry Phospholipid Depolarization Condensed Matter Physics Atomic and Molecular Physics and Optics Coupling (electronics) Cell membrane chemistry.chemical_compound medicine.anatomical_structure Biophysics medicine Lipid bilayer phase behavior Lipid bilayer Mathematical Physics |
| Zdroj: | Physica Scripta. 22:188-192 |
| ISSN: | 1402-4896 0031-8949 |
| DOI: | 10.1088/0031-8949/22/2/017 |
| Popis: | It is suggested that the passage of a nerve impulse might depend on a local phase change in the annular lipid surrounding the channel proteins in the nerve cell membrane. Several protein distributions and configurations are discussed which have cation transmission characteristics that could be dependent on the state of the surrounding lipid. The threshold voltage depolarization, required to trigger these ionic channels, is considered, and it is concluded that this could occur through dipolefield coupling at the heads of the phospholipid molecules. |
| Databáze: | OpenAIRE |
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