Homogenized Macroscale Model and Morphological Microscale Model to Understand the Varying Mechanical Properties of Scar Tissue of Hip Capsule Ligaments Grown Around Different Implant Materials

Autor: Samantha Sanders, Elisa Budyn, Angelina Avgeri, Laurent Sedel, Bertrand Cinquin, P. Bizot
Rok vydání: 2021
Předmět:
Zdroj: JOM. 73:2377-2389
ISSN: 1543-1851
1047-4838
Popis: In total hip arthroplasty, the hip joint is replaced by artificial materials. The fibrous tissue that re-forms around the hip joint after surgery plays an important role in joint stability. Here, the morphological and mechanical properties of the scar tissue that forms around implants composed of either polymer and metal or ceramic are compared with native tissue removed during an initial total hip arthroplasty. Immunohistological analyses of the samples revealed different hierarchical structures of the tissues over three scales: the fiber, the fascicle, and tissue scales. At the tissue scale, microtensile tests were performed on millimetric samples and their nonlinear elastic responses identified by either an exponential law or Ogden third-order constitutive model. At the fiber scale, a patient-specific microscale finite element model was used ,including the measured morphological parameters and distinct Ogden constitutive models for the fiber and matrix composed of a mixture of fibers in ground substance.
Databáze: OpenAIRE
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