| Autor: |
Yvonne J. Rosenberg, Tracy Ordonez, Urjeet S. Khanwalkar, Philip Barnette, Shilpi Pandey, Iara M. Backes, Claire E. Otero, Benjamin S. Goldberg, Andrew R. Crowley, David A. Leib, Mariya B. Shapiro, Xiaoming Jiang, Lori A. Urban, Jonathan Lees, Ann J. Hessell, Sallie Permar, Nancy L. Haigwood, Margaret E. Ackerman |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
mBio. 14 |
| ISSN: |
2150-7511 |
| DOI: |
10.1128/mbio.00341-23 |
| Popis: |
This study compared the ability of several human HIV envelope-directed monoclonal antibodies produced in plants with the same antibodies produced in mammalian cells for their ability to cross monkey and mouse placentas. We found that the two types of antibodies have comparable transfer efficiencies in mice, but they are differentially transferred across macaque placentas, consistent with a two-receptor IgG transport model in primates. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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