Un cas de choc anaphylactique à l'acide tranexamique (Exacyl®)

Autor:	C Ecoffey, Y. Delaval, M.-M. Lucas-Polomeni, P Menestret, P Delaval
Rok vydání:	2004
Předmět:	medicine.medical_specialty Antifibrinolytic business.industry medicine.drug_class Clinical course General Medicine Serum ige Surgery Regimen Anesthesiology and Pain Medicine medicine.anatomical_structure Anesthesia Anesthetic medicine Anaphylactic shock business Tranexamic acid medicine.drug Artery
Zdroj:	Annales Françaises d'Anesthésie et de Réanimation. 23:607-609
ISSN:	0750-7658
DOI:	10.1016/j.annfar.2004.04.012
Popis:	A 72-year-old male patient was scheduled for coronary artery bypass graft surgery because of severe three-vessel disease. Induction of anaesthesia was uneventful. Following bolus infusion of tranexamic acid (Exacyl), the patient presented clinical signs consistent with anaphylactic shock. Surgery was postponed and the patient recovered without sequaelae. Allergological investigations (cutaneous tests, serum IgE concentrations, in vitro histamine-release tests) suggest that this is the first reported case of anaphylactic shock to tranexamic acid. Several weeks later, the patient underwent surgery with a similar anaesthetic regimen and the clinical course was uneventful.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::577b00246acf1f01b616981079c1dc86 https://doi.org/10.1016/j.annfar.2004.04.012 Zobrazit plný text záznamu Full Text from ScienceDirect