Biocompatibility polyelectrolyte coating with water-enabled self-healing ability
| Autor: | Zhiqiang Wang, Lijuan Wang, Long Wang, Lanlan Zang, Quanping Su, Abdelrahman Elbaz, Fengyuan Che, Zhu Yanxi, Qianqian Zou |
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| Rok vydání: | 2018 |
| Předmět: |
Materials science
Biocompatibility Hydrogen bond General Chemical Engineering Nanoparticle 02 engineering and technology General Chemistry engineering.material 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Polyelectrolyte 0104 chemical sciences Chitosan chemistry.chemical_compound chemistry Coating Chemical engineering Self-healing engineering Molecule 0210 nano-technology |
| Zdroj: | Journal of the Taiwan Institute of Chemical Engineers. 91:130-137 |
| ISSN: | 1876-1070 |
| Popis: | A biocompatibility polyelectrolyte coating capable of self-healing damages was developed via Layer-by-Layer self-assembly, a synthetic strategy that alternatively assembles layers of Chitosan (CS) and hyaluronic acid (HA). The reversible interactions of the hydrogen bonding formed between CS and HA can be dynamically associated/dissociated with water, imparting the CS/HA polyelectrolyte coating with substantially improved self-healing property and significantly decreasing micro-cracks and their associated concerns. Also, through structural changes induced during the freeze-drying and self-healing processes, not only can different kinds of drug molecules be easily loaded into CS/HA polyelectrolyte coating but also a variety of nanoparticles. These features provide the CS/HA polyelectrolyte coating with extend lifespan, enhanced reliability, and considerable promise for applying in novel functional biomedical materials. |
| Databáze: | OpenAIRE |
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