PS15 - 76. The Toll like receptor 3 in adipose tissue determines local inflammation

Autor:	Henrique J. Jansen, Edwin J.P. van Asseldonk, Tim B. Koenen, Rinke Stienstra, M.G. Netea, Cees J. Tack
Rok vydání:	2011
Předmět:	Toll-like receptor Innate immune system viruses virus diseases Adipose tissue hemic and immune systems chemical and pharmacologic phenomena Inflammation Endogeny Stimulation Biology Immunology TLR3 medicine medicine.symptom Receptor
Zdroj:	Nederlands Tijdschrift voor Diabetologie. 9:142-143
ISSN:	1876-6242 1567-2743
Popis:	Obesity is associated with inflammation at the level of the fat tissue, but the initiating mechanisms are unclear. Toll like receptors (TLRs) are at the frontline of innate immunity. TLRs sense specific exogenous and endogenous ligands. TLR3 typically recognizes double-stranded RNA. Although expression of TLR3 in adipocytes has been shown, the functional effects of TLR3 stimulation in adipocytes are unknown.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5748093ccfed8f5690f6928bd611de20 https://doi.org/10.1007/s12467-011-0101-9 Zobrazit plný text záznamu Full text from SpringerLink