Skin penetration by indomethacin is enhanced by use of an indomethacin/smectite complex

Autor: Toshio Takahashi, Toshihiro Sugafuji, Ito Taketoshi, Miyuki Maruyama, Yutaka Ohwa
Rok vydání: 2001
Předmět:
Zdroj: Journal of Supramolecular Chemistry. 1:217-219
ISSN: 1472-7862
DOI: 10.1016/s1472-7862(02)00028-x
Popis: The effect of indomethacin/smectite complex on skin penetration enhancement of indomethacin in cataplasm has been examined. Complexation with smectite increases the stability of amorphous indomethacin resulting in a complex that is more skin-permeable than the free drug.
Databáze: OpenAIRE