Skin penetration by indomethacin is enhanced by use of an indomethacin/smectite complex
Autor: | Toshio Takahashi, Toshihiro Sugafuji, Ito Taketoshi, Miyuki Maruyama, Yutaka Ohwa |
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Rok vydání: | 2001 |
Předmět: | |
Zdroj: | Journal of Supramolecular Chemistry. 1:217-219 |
ISSN: | 1472-7862 |
DOI: | 10.1016/s1472-7862(02)00028-x |
Popis: | The effect of indomethacin/smectite complex on skin penetration enhancement of indomethacin in cataplasm has been examined. Complexation with smectite increases the stability of amorphous indomethacin resulting in a complex that is more skin-permeable than the free drug. |
Databáze: | OpenAIRE |
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