Steroids from the South China Sea Gorgonian Coral Muricella flexuosa
Autor: | Wang Yifei, Fei He, Kai-Sheng Liu, Ping Wang, Shu-Hua Qi, Li-Si Huang |
---|---|
Rok vydání: | 2011 |
Předmět: | |
Zdroj: | Zeitschrift für Naturforschung B. 66:635-640 |
ISSN: | 1865-7117 0932-0776 |
DOI: | 10.1515/znb-2011-0612 |
Popis: | Four new steroidal glycosides and a new steriod linked with a 4-hydroxyphenylmethylene group, namely muricellasteroids A- E (1 - 5), together with one known steroidal glycoside analog, 22α,2ʹ,3ʹ,4ʹ-O-tetraacetyl-27-O-[β -D-arabino-pyranosyl-oxy]-20β -hydroxy-cholest-4- ene-3-one (6), were isolated from the EtOH/CH2Cl2 extracts of the South China Sea gorgonian coral Muricella flexuosa. The structures of 1 - 5 were established by means of 1D- and 2D-NMR and other spectroscopic analyses. Compounds 1 - 3 and 5 - 6 showed moderate cytotoxicity against A375, K562, and A549 cancer cell lines. |
Databáze: | OpenAIRE |
Externí odkaz: |