Diastereoselective synthesis of highly functionalized tetrahydropyrans from the cyclic vinyl acetal with aldehydes mediated by lewis acid catalyst

Autor:	Jae Kyun Lee, Jongho Lee, Chan-Mo Yu, Ha-Soon Choi, Wonhee Jung
Rok vydání:	1995
Předmět:	chemistry.chemical_compound Chemistry Pyran Organic Chemistry Drug Discovery Acetal Organic chemistry Tetrahydropyran Ring (chemistry) Biochemistry Lewis acid catalysis
Zdroj:	Tetrahedron Letters. 36:8255-8258
ISSN:	0040-4039
DOI:	10.1016/0040-4039(95)01771-9
Popis:	A new method for constructing substituted tetrahydropyrans from the conjunction of 6-ethylthio-3,4-dihydro-2-methoxy-2 H -pyran with aldehydes in the presence of 10 mol % SnCl 4 is described. This reaction is highly stereocontrolled and allows various functionalities to be incorporated at tetrahydropyran ring.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::571581320cb15e509fa6a7ecbdb1ce3f https://doi.org/10.1016/0040-4039(95)01771-9 Zobrazit plný text záznamu Full Text from ScienceDirect