Effect of Combined Heat killed Probiotic and Wheat Bran on Gastrointestinal Symptoms in Hemodialysis Children

Autor: Seham Mohamed Ramadan, Doaa Mohamed Youssef, May Abd Alfattah Neemat-Allah, Aly Abdel-Rahman Yousef, Ali Mohamed Abou Zeid, Yasmeen Ghanem Zakaria
Rok vydání: 2019
Předmět:
Zdroj: GEGET. 14:8-14
ISSN: 2636-3658
DOI: 10.21608/geget.2019.38015
Popis: Background Gastrointestinal (GIT) disturbances are recorded in patients with end stage renal diseases (ESRD) frequently, killed probiotic was reported in to decrease GIT problems many other diseases ; So The aim of our study is to evaluate whether a combination of heat killed probiotic and wheat bran affect the presence and severity of gastrointestinal symptoms (GIS) in hemodialysis children Patients and methods Our study was Open label uncontrolled clinical trial conducted on 35 pediatric patients on regular hemodialysis for end stage renal disease. Every patient received one sachet of killed probiotic and wheat bran twice daily for two months. Assessment of GIT symptoms were done one month before administration of the drug, then follow them for two months during intervention then reassess the symptoms. Result We found that combined heat killed probiotic +wheat bran administration to hemodialysis children produced significant differences in urea, Hb and Po4 levels compared to baseline levels, in addition children produced highly significant decrease in all gastrointestinal symptoms (P
Databáze: OpenAIRE