| Autor: |
Lorena Monteiro, Rafael Lessa da Costa, Liszt Palmeira de Oliveira, Max R.F Ramos, Claudia Adelino Espanha, Renan Bonancim, Luiz Fernando Nogueira Simvoulidis, Cristiane da Cruz Lamas, Eduardo Costa Freitas da Silva, João Victor Weber |
| Rok vydání: |
2021 |
| Předmět: |
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| DOI: |
10.21203/rs.3.rs-403577/v1 |
| Popis: |
Background: some studies have shown that superinfection during pandemics may have contributed to high mortality. Our objective is to identify the frequency, types and aetiology of superinfections in patients with Covid-19 admitted to the intensive care unit (ICU) and to evaluate the results of ICU stay, duration of mechanical ventilation (MV) and hospital mortality.Methods: retrospective cohort of adult patients admitted to the ICU for more than 48 hours between March to May 2020. Comparisons of groups with and without ICU- acquired infection were established.Results: a total of 191 patients with laboratory-confirmed COVID-19 were included and 57 patients had 97 secondary infectious events. Most frequent agents were Acinetobacter baumannii (28.9%), Pseudomonas aeruginosa (22.7%) and Klebsiella pneumoniae (14.4%); multi-drug resistance was present in 96% Acinetobacter and in 57% K.pneumoniae. The most prevalent infection was ventilator-associated pneumonia (VAP) in 57.9% of patients with bacterial superinfection, or 17.3% of all COVID-19 patients admitted to ICU, followed by tracheobronchitis, in 26.3%. Patients with superinfection had a longer ICU stay (40.0 vs. 17; p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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