Rapidly mutating Y-STRs population data in Taiwan and haplotype probability estimation for forensic purposes

Autor: Meng-Yi Chen, Fang-Chin Wu, Huei-Yu Lai, Chang-En Pu, Chin-Wen Ho
Rok vydání: 2015
Předmět:
Zdroj: ICCST
DOI: 10.1109/ccst.2015.7389717
Popis: A total of 656 unrelated males from Taiwan population were typed with 13 rapidly mutating Y-chromosome short tandem repeat (Y-STR) markers: DYF399S1, DYF387S1, DYS570, DYS576, DYS518, DYS526a+b, DYS626, DYS627, DYF403S1a+b, DYF404S1, DYS449, DYS547 and DYS612. 655 haplotypes of the RM 13 Y-STRs were obtained which only one haplotype was shared by two individuals. The combined haplotype diversity of the RM 13 Y-STRs was 0.9985. Allele frequencies for each locus are reported with nomenclature based on sequence analysis identical with published paper and recommendation from ISFG. Allele variances were observed in several loci when compared with allelic ladder by PCR duplicated. According to SWDGAM guidelines for Y-STR typing by forensic DNA laboratories, we illustrated the Y-STRs profile probability estimation by using Taiwan population database.
Databáze: OpenAIRE