A super hydrophilic silsesquioxane-based composite for highly selective adsorption of glycoproteins
| Autor: | Huiyan Shen, Xuwei Chen, Yue Zhang, Jian-Hua Wang, Yu-Ting Zhuang |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
biology Chemistry Composite number 02 engineering and technology Polymer 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Silsesquioxane 0104 chemical sciences Analytical Chemistry Catalysis chemistry.chemical_compound Ovalbumin Adsorption Polymerization Polymer chemistry biology.protein 0210 nano-technology Glycoprotein |
| Zdroj: | Microchimica Acta. 184:1037-1044 |
| ISSN: | 1436-5073 0026-3672 |
| DOI: | 10.1007/s00604-017-2100-z |
| Popis: | The authors have prepared a super-hydrophilic polymer consisting of a poly-polyhedral oligomeric silsesquioxane (POSS)-formaldehyde (PPF) composite. The polymerization process does not require a catalyst and results in a material with excellent hydrophilic properties and abundant functional groups. The PFF composite, even if not chemically modified, can selectively bind glycoproteins due to strong hydrophilic interactions. It is shown that glycoproteins can be selectively captured by the composite that has a binding capacity as large as 542 mg g−1 for the model protein ovalbumin. The PPF was applied to the selective capture and isolation of ovalbumin from complex biological samples. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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