Efficient preparation of 2,4-methanoproline

Autor:	James M. Hulsizer, Jeffrey S. Albert, Jeffrey G. Varnes, Gary L. Moore, G. Scott Lehr
Rok vydání:	2010
Předmět:	chemistry.chemical_compound chemistry Hydrochloride Yield (chemistry) Organic Chemistry Drug Discovery Organic chemistry Biochemistry Serine methyl ester
Zdroj:	Tetrahedron Letters. 51:3756-3758
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2010.05.054
Popis:	Using a modification of the route described by Clardy and Hughes et al., 2,4-methanoproline hydrochloride ( 1 ) was prepared in four steps and 70% overall yield from dl -serine methyl ester.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::56cac2272744a3a86dc5a103ebf73cf2 https://doi.org/10.1016/j.tetlet.2010.05.054 Zobrazit plný text záznamu Full Text from ScienceDirect