| Autor: |
Samuel Klempner, Brandon Huffman, Vasily Aushev, Griffin Budde, Joseph Chao, Farshid Dayyani, Diana Hanna, Gregory Botta, Daniel Catenacci, Steven Maron, Shifra Krinshpun, Shruti Sharma, Giby George, Meenakshi Malhotra, Adham Jurdi, Solomon Moshkevich, Alexey Aleshin, Pashtoon Kasi |
| Rok vydání: |
2022 |
| Popis: |
Personalized and tumor-informed, circulating tumor DNA (ctDNA) analysis allows for postoperative risk stratification in patients with curatively treated esophagogastric cancers (EGC). In this retrospective analysis of real-world data, ctDNA levels were analyzed in 295 EGC patients using a personalized multiplex PCR-based next generation sequencing assay. Postoperative ctDNA was significantly associated with shorter recurrence-free survival. In multivariate analyses, ctDNA status was the most significant prognostic factor associated with disease recurrence. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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