Synthèses D'indoles Et d'Indolizines Marqués Spécifiquement par 13C dans le Cycle Pentagonal

Autor:	M. Corval, M.F. Lautie
Rok vydání:	1982
Předmět:	Indole test Propanol chemistry.chemical_compound chemistry Stereochemistry Organic Chemistry Drug Discovery Radiology Nuclear Medicine and imaging Indolizine Biochemistry Spectroscopy Analytical Chemistry
Zdroj:	Journal of Labelled Compounds and Radiopharmaceuticals. 19:1011-1020
ISSN:	0362-4803
DOI:	10.1002/jlcr.2580190903
Popis:	The syntheses of 2-13C and 3-13C indoles and indolizines and 1-13C indolizine are described. They are obtained from 1-13C bromoacetaldehyde on (2-pyridyl) ethylacetate for 2-13C indolizine, and through cyclisations of suitably labelled intermediates:o-formotoluidide for 2-13C indole, o,β-dinitrostyrene for 3-13C indole, and 3-(2-pyridyl)-1 propanol for 3-13C and for 1-13C indolizines. Every position is more than 90% 13C- labelled.
Databáze:	OpenAIRE
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