Synthesis, Characterization of Cu(I) Complex of Thiosemicarbazone Ligand and Antibacterial Activity of Cu(I) Complex

Autor: Ayman S. Eldourghamy, Nashwa M. H. Rizk, S. A. Aly, Magda A. El-Salamony, Asmaa S. Hashad
Rok vydání: 2018
Předmět:
Zdroj: Research Journal of Applied Biotechnology. 4:30-38
ISSN: 2356-9433
Popis: Novel complex of Cu(I) of ligand 2-(Anilinoacetyl)-N-phenylhydrazine-1-carbothioamide (H2L) has been synthesized and characterized by 1HNMR, IR, elemental analyses, molar conductance, UVvisible spectra, magnetic susceptibility measurements and thermogravimetric analysis (TGA/DTG). The result confirmed that the ligand behaved as neutral bidentate, coordination take place via carbonyl oxygen(C=O) and N(2)H groups. Copper complex is more thermally stable than free ligand. Copper(I) complexes is mononuclear, adopt octahedral geometry. The ligand and complex have been tested for their inhibitory effect on the growth of bacteria against gram-positive (Streptococcus pyogenes) and gram negative (Escherichia coli). The results proved that the copper complex has less potent antibacterial as compared to the ligand.
Databáze: OpenAIRE