Prevalence of silent atrial fibrillation in high-risk patients - preliminary results from a European three-country handheld ECG-screening study
| Autor: | S Sieghartsleitner, A Pervez Sheikh, Mårten Rosenqvist, J Bech Jensen, H Puererfellner, J Lillqvist, Ulrik Dixen, Johan Engdahl, T Hendrikx, I Lund |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
High risk patients business.industry Cardiac arrhythmia Atrial fibrillation medicine.disease law.invention Stroke risk law Physiology (medical) Heart failure Internal medicine Ischemic stroke medicine Cardiology Artificial cardiac pacemaker Cardiology and Cardiovascular Medicine business Screening study |
| Zdroj: | EP Europace. 23 |
| ISSN: | 1532-2092 1099-5129 |
| DOI: | 10.1093/europace/euab116.156 |
| Popis: | Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): Helsefonden Lilly and Herbert Hansens Foundation Introduction Patients with atrial fibrillation (AF) should in most cases be offered prophylactic anticoagulation treatment to prevent a stroke. However, the arrhythmia can appear without symptoms, so-called silent AF. Even without symptoms AF constitutes a risk for stroke. Purpose To screen high-risk patients with diabetes type 2 (DMII) or heart failure (CHF) for silent AF. Methods We included patients > 64 years with either DMII or CHF from out-patient clinics and local health centers. Exclusion criteria were known AF, anticoagulation treatment, recent stroke, or an implanted pacemaker or ICD. Patients were recruited from a total of eleven study centers in three countries. All underwent 14-days of intermittent ECG screening with a handheld ECG recording four times each day; the recordings were digitally stored. AF was diagnosed in cases of irregular heart rhythm and absence of P waves on at least one recording (thirty seconds) or on at least two recordings for a minimum of ten seconds. Results In total, 813 patients were included, 541 of these with DMII. The mean age was 73,4 years ± 5,8 SD, 40,7% of the patients were female. In the DMII group thirteen patients (2.4%) were diagnosed with silent AF and offered anticoagulation. In the CHF group six (2.2%) patients had diagnosed silent AF on the handheld ECG. The prevalence of AF increased with increasing age, see Table 1. Thus, in the youngest group AF was diagnosed in 1.3% of the patients compared to 3.9 % in the age group 75 years or older. Conclusions Screening for silent AF in high-risk patients with DMII or CHF seems worthwhile, especially in patients 75 years or older. Abstract Figure. ECG with atrial fibrillation |
| Databáze: | OpenAIRE |
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