Extended Release Matrix Tablets of Nateglinide: Formulation and In vitro Evaluation

Autor:	K. Akhila, Y. Krishna Reddy
Rok vydání:	2020
Předmět:	chemistry.chemical_classification Materials science Chromatography Polymer Nateglinide Bioavailability Matrix (chemical analysis) chemistry medicine Extended release Dissolution Extended release tablets Xanthan gum medicine.drug
Zdroj:	Asian Journal of Pharmaceutical Research. 10:101
ISSN:	2231-5691 2231-5683
DOI:	10.5958/2231-5691.2020.00019.2
Popis:	In the present study to establish oral extended release tablets of Nateglinide using different polymers. The tablets were prepared using Xanthan gum, HPMC K15, Carbapol 934 using different polymers to impart extended release study. Tablets were evaluated by different parameters such as weight variation, content uniformity, thickness, hardness, IR spectral analysis, in vitro release studies and kinetic analysis of dissolution data. The present study concluded that extended release tablets of Nateglinde can be a good way to increases the dissolution and bioavailability of Nateglinde.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::56aaac696d44557901170c95ac9a1002 https://doi.org/10.5958/2231-5691.2020.00019.2 Zobrazit plný text záznamu