Etiology of rickets in Nigerian children
| Autor: | Lawrence M. Oginni, O. A. Oyelami, M. Worsfold, CA Sharp, D.E. Powell, M.W.J. Davie |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Pediatrics business.industry Active rickets chemistry.chemical_element Rickets Calcium medicine.disease Control subjects vitamin D deficiency Endocrinology chemistry El Niño Internal medicine Pediatrics Perinatology and Child Health Healthy control medicine Etiology business |
| Zdroj: | The Journal of Pediatrics. 128:692-694 |
| ISSN: | 0022-3476 |
| DOI: | 10.1016/s0022-3476(96)80137-5 |
| Popis: | We studied 26 Nigerian children with active rickets (13 boys, 13 girls), aged 1 to 5 years, and compared results of biochemical studies with those of healthy control subjects. The plasma 1,25-dihydroxyvitamin D level was elevated (568 ± 317 pmol/L) and the 25-hydroxyvitamin D level was low (36 ± 28 nmol/L) in the children with rickets compared with the control subjects (369 ± 134 nmol/L and 69 ± 22 nmol/L, respectively). The results suggest that rickets in Nigeria is largely the result of calcium deficiency and that vitamin D deficiency and possibly end organ resistance may be contributory factors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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