Plasma lipids and urinary albumin excretion rate in Type 1 diabetes mellitus: the EURODIAB IDDM Complications Study
| Autor: | M. B. Mattock, N. Cronin, P. Cavallo-Perin, B. Idzior-Walus, G. Penno, S. Bandinelli, E. Standl, A. Kofinis, J. H. Fuller, null The Eurodiab Iddm Complications Stu |
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| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
Type 1 diabetes Proteinuria Cholesterol business.industry Endocrinology Diabetes and Metabolism Urinary system Albumin medicine.disease Excretion chemistry.chemical_compound Endocrinology chemistry Internal medicine Diabetes mellitus Internal Medicine medicine Microalbuminuria medicine.symptom business |
| Zdroj: | Diabetic Medicine. 18:59-67 |
| ISSN: | 0742-3071 |
| DOI: | 10.1046/j.1464-5491.2001.00411.x |
| Popis: | SUMMARY Aims To examine the relationship between increased urinary albumin excretion rate and fasting plasma lipids among male and female respondents to the EURODIAB IDDM Complications Study, and attempt to explain inconsistencies in previous reports. Methods A cross-sectional study of 3250 randomly selected Type 1 diabetic patients from 31 diabetes clinics in 16 European countries was carried out between 1989 and 1990. Plasma lipids and urinary albumin were measured centrally. The present analysis was confined to the subgroup of 2205 patients attending after a 10–12 h overnight fast. Mean age was 33 years (sd 10) and mean duration of Type 1 diabetes mellitus was 15 years (sd 9). Results The prevalence of microalbuminuria (24-h urinary albumin excretion rate 20–200 μg/min) was 21.7% (95% confidence interval 19.9–23.5) and macroalbuminuria (24-h urinary albumin excretion rate > 200 μg/min) 7.8% (6.6–9.0). In comparison to patients with normal urinary albumin excretion rate ( |
| Databáze: | OpenAIRE |
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