Polymorphism of Platelet Membrane Glycoprotein IIIa: Human Platelet Antigen 1b (HPA-1b/PlA2) Is an Inherited Risk Factor for Premature Myocardial Infarction in Coronary Artery Disease

Autor:	G. Giers, Rüdiger E. Scharf, Rainer B. Zotz, Markus Nauck, Winfried März, Beate Maruhn-Debowski, Bernhard R. Winkelmann
Rok vydání:	1998
Předmět:	medicine.medical_specialty biology business.industry Hematology medicine.disease Thrombosis Human platelet antigen Coronary artery disease Internal medicine medicine biology.protein Cardiology Platelet Myocardial infarction Age of onset Complication business Prospective cohort study
Zdroj:	Thrombosis and Haemostasis. 79:731-735
ISSN:	2567-689X 0340-6245
DOI:	10.1055/s-0037-1615054
Popis:	SummaryConflicting results of an association between the human platelet antigen 1b (HPA-1b or PlA2) allele and the risk of myocardial infarction and coronary artery disease have been reported. To assess the reason for this discrepancy, we determined the HPA-1 genotype in 298 men who had undergone coronary angiography, including 124 individuals with myocardial infarction, 83 individuals with coronary artery disease but no history of myocardial infarction, and 91 control patients. Among patients with acute or recent onset myocardial infarction (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5698de0a3559fec605be27e70cc19743 https://doi.org/10.1055/s-0037-1615054 Zobrazit plný text záznamu