ESTIMATION OF THYROID PROFILE AND SERUM FASTING INSULIN IN NEWLY DETECTED HYPOTHYROID ADULTS: A CASE CONTROL STUDY

Autor:	L. Shaini Devi, Sangeeta N, Pinky Karam, Victoria Kshetrimayum, Usha S M R
Rok vydání:	2021
Předmět:	medicine.medical_specialty Endocrinology medicine.anatomical_structure endocrine system diseases business.industry Internal medicine Thyroid medicine Case-control study business hormones hormone substitutes and hormone antagonists Fasting insulin
Zdroj:	INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH. :50-52
DOI:	10.36106/ijsr/6404685
Popis:	Background: Thyroid hormone inuences glucose homeostasis by modications of the circulating insulin levels and peripheral tissues uptake of glucose. Thyroid function has been associated with insulin resistance. There is infrequent information about thyroid function in relation with glucose homeostasis in young adults. Objective: To evaluate the thyroid prole, fasting serum insulin, HOMA-IR, Fasting blood sugar among newly detected hypothyroid adults (cases) in comparison with normal healthy adults (controls). Methodology: A case control study of 164 subjects was carried out on hypothyroid adults (n=82) and controls (n=82), general medicine OPD, RRMC & hospital, Bengaluru. Fasting blood samples were taken. Thyroid prole, serum fasting insulin was done with CLIA. HOMA-IR was employed to assess the level of insulin resistance. Results: The study subjects with mean age of 35 years and female predominance. TSH levels were higher in cases as compared to controls (p
Databáze:	OpenAIRE
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