Autor:	Shiroshi Shibuya, Tsutomu Yokomatsu, Keiichi Fujii, Takehiro Yamagishi
Rok vydání:	2006
Předmět:	Stereochemistry Dihydroxylation Chemistry Organic Chemistry Drug Discovery Enantioselective synthesis Organic chemistry Regioselectivity Optically active Biochemistry Amination Catalysis
Zdroj:	Tetrahedron. 62:54-65
ISSN:	0040-4020
DOI:	10.1016/j.tet.2005.09.126
Popis:	Phosphonic acid analogues of acylcarnitine were prepared in an optically active form expecting CPT I inhibitory activities. The synthetic methodology was based on catalytic asymmetric dihydroxylation of β,γ-unsaturated phosphonates and subsequent regioselective amination via the cyclic sulfates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::56407cd3327493fbc4dfd1000127009c https://doi.org/10.1016/j.tet.2005.09.126 Zobrazit plný text záznamu Full Text from ScienceDirect