α-β-didehydrotryptophan as a surrogate for α-methyltryptophan in CCK ‘peptoids’ related to CI-988

Autor:	David Christopher Horwell, Martyn Clive Pritchard, J.M. Eden
Rok vydání:	1993
Předmět:	Chemistry digestive oral and skin physiology Organic Chemistry Clinical Biochemistry Pharmaceutical Science digestive system Biochemistry Combinatorial chemistry CI-988 Drug Discovery Molecular Medicine Receptor Molecular Biology hormones hormone substitutes and hormone antagonists
Zdroj:	Bioorganic & Medicinal Chemistry Letters. 3:989-992
ISSN:	0960-894X
Popis:	The design and synthesis of high affinity α,β-didehydrotryptophan substituted CCK ligands is described. Ligands selective for both the CCK-A and CCK-B receptor subtypes have been prepared.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5627044348b8a6ddeb775a7b49f53000 https://doi.org/10.1016/s0960-894x(00)80273-5 Zobrazit plný text záznamu