A Convenient Procedure for Moderate-scale Rothemund Synthesis of Lipophilic Porphyrins: an Alternative to the Adler–Longo and Lindsey Methodologies

Autor:	Pall Thordarson, Maxwell J. Crossley, J. Patrick Bannerman, Philip Maynard
Rok vydání:	1998
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Acid catalysis chemistry Porphyrin synthesis Organic chemistry General Chemistry Aldehyde Porphyrin Pyrrole
Zdroj:	Journal of Porphyrins and Phthalocyanines. :511-516
ISSN:	1099-1409 1088-4246
DOI:	10.1002/(sici)1099-1409(199811/12)2:6<511::aid-jpp102>3.0.co;2-e
Popis:	Rothemund synthesis of porphyrins is conveniently achieved using p-toluenesulfonic acid-catalysed reaction between pyrrole and aldehyde with azeotropic removal of the water formed in the reaction. These conditions are suitable for moderate-scale reactions and involve an easy work-up. In this way, 5,10,15,20-tetraheptylporphyrin (2), 5,10,15,20-tetrakis(3,5-di-tert-butylphenyl)porphyrin (3), 5,10,15,20-tetra-tert-butylporphyrin (4) and 5,10,15,20-[pyromellitoyl(tetrakis-o-oxyethoxyphenyl)]por-phyrin (5) were prepared in moderate to good yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::561690581cdc3c835a7330d19e433a30 https://doi.org/10.1002/(sici)1099-1409(199811/12)2:6<511::aid-jpp102>3.0.co Zobrazit plný text záznamu Plný text