Gender differences in risk of myocardial infarction and stroke in population with sleep disorders in Russia / Siberia: population-based study MONICA-psychosocial

Autor: D Panov, A Gafarova, E Gromova, I Gagulin, V. V. Gafarov
Rok vydání: 2021
Předmět:
Zdroj: European Journal of Preventive Cardiology. 28
ISSN: 2047-4881
2047-4873
DOI: 10.1093/eurjpc/zwab061.205
Popis: Funding Acknowledgements Type of funding sources: None. Objectives To determine the gender differences in the effect of sleep disorders on risk of myocardial infarction (MI) and stroke in population 25-64 years over 16 years of follow-up. Methods Under the third screening of WHO program MONICA -Psychosocial a random representative sample of both gender aged 25- 64 years in Novosibirsk was examined in 1994 (n = 1346, male 48.8%, mean age 44,9 ± 0,4 years). The sleep assessment was performed using the Jenkins Sleep Questionnaire. There were 15 cases of new-onset MI in women and 30 in men, new-onset stroke 35 cases in women and 22 in men from 1994 to 2010. Results In an open population aged 25-64 years 48.6% of men and 65.9% of women had sleep disorders (p< 0.001). Univariate analysis showed 2.4-fold risk of MI in those males with SD over 16-year of follow-up (95%CI 1.1-5.3; p< 0.05) but not for women. MI risk was higher in those men who were never married, divorced or widowed (p for all Conclusions Sleep disorders is a risk factor of MI in men only and stroke for both gender and negative social gradient increases cardiovascular risk.
Databáze: OpenAIRE