| Popis: |
Red blood cell (RBC) transfusion is a life-saving therapy for many patients, but it is a prominent part of therapy for thalassemia, sickle cell disease, and patients with malignancies. RBC alloimmunization is a therapy-limiting complication of RBC transfusion, and its prevalence and causes are linked most to the amount of exposure to allogeneic transfusions, but antigen disparity between donor and recipient as well as recipient genetic predisposition and concomitant therapy also factor into how likely a patient is to experience this complication. |
