Comparison between leukocyte esterase activity and histopathological examination in identifying chorioamnionitis
| Autor: | Bernolian Nuswil, Ramadanti Afifa, Novianesari Putri Healthireza, Theodorus, Maulani Henni |
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| Rok vydání: | 2018 |
| Předmět: |
Embryology
Pathology medicine.medical_specialty business.industry Obstetrics and Gynecology Histopathological examination Chorioamnionitis medicine.disease 03 medical and health sciences Leukocyte esterase 0302 clinical medicine 030225 pediatrics Pediatrics Perinatology and Child Health medicine 030212 general & internal medicine business |
| Zdroj: | Case Reports in Perinatal Medicine. 7 |
| ISSN: | 2192-8959 |
| DOI: | 10.1515/crpm-2017-0045 |
| Popis: | Objective To compare the sensitivity and specificity of leukocyte esterase activity (LEA) to histopathological examination in diagnosing chorioamnionitis. Methods We compared the diagnostic tests performed at Dr. Mohammad Hoesin Hospital, Palembang, Indonesia, from September 2015 to April 2016. Ninety-one pregnant women were included in the study. The LEA and histopathological examination were carried out with neonatal sepsis the main outcome. Data were analyzed using the SPSS version 21.0 and MedCalc statistics. Results Chorioamnionitis was detected in 54 (77.1%) patients with a gestational age ≥37 weeks and in 16 (22.9%) patients with a gestational age 0.5 was able to significantly predict chorioamnionitis with 98.6% sensitivity and 95.2% specificity, providing better accuracy in diagnosing chorioamnionitis in the preterm pregnancy group. Conclusion LEA had a very good predictive value for chorioamnionitis with better accuracy in diagnosing chorioamnionitis in preterm pregnancy. |
| Databáze: | OpenAIRE |
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