Should ICSI be the treatment of choice for all cases of in-vitro conception?

Autor: Leonardo Rinaldi, Steve Green, Irfan Aslam, Lawrence Gobetz, Rosella Lisi, Judy Timson, Merwyn Jacobson, Alison Campbell, Simon Fishel, F Lisi
Rok vydání: 2000
Předmět:
Zdroj: Human Reproduction. 15:1278-1283
ISSN: 1460-2350
0268-1161
DOI: 10.1093/humrep/15.6.1278
Popis: The objective of this study was to examine different clinical scenarios of in-vitro conception, viz. fertilization with conventional IVF, IVF with high insemination concentration (HIC) and intracytoplasmic sperm injection (ICSI), and assess on a sibling oocyte comparison the hypothesis that ICSI should be performed in all cases requiring in-vitro conception. ICSI with husband's spermatozoa had a higher incidence of fertilization as compared with IVF or IVF with HIC with donor spermatozoa (if previous failure of fertilization had occurred) for unexplained infertility. Similarly, ICSI with husband's spermatozoa had as high an incidence of fertilization as IVF with donor spermatozoa for patients with severe oligozoospermia, asthenozoospermia and/or teratozoospermia, even when the spermatozoa were not selected for their morphology. Two studies were performed to assess ICSI in potential oocyte-related failure of IVF, viz. when fertilization occurred in >50% of oocytes for one group of patients, and in
Databáze: OpenAIRE