Evolución de la adherencia al tratamiento antirretoviral del 2000 al 2008

Autor: M.J. Martínez-Bengoechea, A. Urrutia Losada, J. Mayo Suárez, A. López de Torre Querejazu, E. Martinez Gutíerrez, O. Ibarra Barrueta
Rok vydání: 2010
Předmět:
Zdroj: Farmacia Hospitalaria. 34:279-283
ISSN: 1130-6343
Popis: Objectives: To evaluate antiretroviral treatment adherence in the HIV patient cohort of our hospital and observe their evolution over a 9-year period; also to determine the individual pattern of adherence over time. Methods: Descriptive study of the evolution of average annual adherence and the annual percentage of adherent patients greater than 95% from 2000 to 2008. We analysed the individual pattern of adherence over time and patients were classified into consistently adherent, consistently non-adherent, and fluctuating. Results: In the analysis of 577 patients, baseline adherence was significantly greater in naive patients with respect to those who were pre-treated. Average annual adherence increased slightly and stayed at values around 95%. As with the percentage of patients with adherence greater than 95%, which increased from 64% in 2000 to 79% in 2008. In terms of the individual pattern of adherence over time, of the 468 patients analysed, the majority (59%) were consistently adherent, 4% non-adherent, and the rest (37%) fluctuated in their adherence. Conclusions: In our cohort the overall adherence values maintained themselves over time and even show a positive trend, likely the result of systematic monitoring of adherence and implementation strategies to maintain adherence.
Databáze: OpenAIRE