Submucosal Injection of Mitomycin C in a Case of Vanishing Bronchus After Lung Transplant
| Autor: | Mehmet Furkan Sahin, Alkin Yazicioglu, Muhammet Ali Beyoglu, Erdal Yekeler, Sinan Turkkan |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Transplantation
medicine.medical_specialty Bronchus Lung Bronchial wall medicine.diagnostic_test business.industry Mitomycin C Submucosal injection respiratory system medicine.disease respiratory tract diseases Surgery Stenosis medicine.anatomical_structure Bronchoscopy medicine Complication business |
| Zdroj: | Experimental and Clinical Transplantation. 20:627-629 |
| ISSN: | 2146-8427 1304-0855 |
| Popis: | Segmental nonanastomotic stenosis, also known as vanishing bronchus intermedius syndrome (or simply, "vanishing bronchus"), is a rare complication that can occur after a lung transplant. It usually occurs in the first posttransplant year and often develops in the intermediate bronchus. Definitive diagnosis is established by bronchoscopy. The treatment management primarily includes bronchoscopic dilatation and stenting. In patients who do not benefit from these applications, lung resection or retransplant may be indicated. Our 58-year-old patient developed vanishing bronchus after lung transplant, and recurrence could not be prevented despite repeated bronchoscopic interventions. We applied submucosal mitomycin C injection to the bronchial wall of the stenotic segment and achieved significant benefit for reduction of recurrence. Our aim was to document the first reported case of a patient with vanishing bronchus who was treated with submucosal administration of mitomycin C, a strong fibroblast inhibitor, and to report the outcomes of submucosal mitomycin C administration with regard to recurrence. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|