Developments in the synthesis of new functionalized bisphosphonate drug candidates such as cyclic prodrugs
| Autor: | Frank H. Ebetino, J. Joly, Mark W. Lundy, Roy L. M. Dobson, Roslin Russell, V. A. Pavlov, A. W. Mazur |
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| Rok vydání: | 2016 |
| Předmět: |
Drug
Chemistry media_common.quotation_subject medicine.medical_treatment Organic Chemistry 030209 endocrinology & metabolism Bisphosphonate Prodrug 010403 inorganic & nuclear chemistry 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences Inorganic Chemistry 03 medical and health sciences 0302 clinical medicine medicine media_common |
| Zdroj: | Phosphorus, Sulfur, and Silicon and the Related Elements. 191:1504-1508 |
| ISSN: | 1563-5325 1042-6507 |
| Popis: | A new series of bisphosphonic acids bearing nitrogen containing heterocycles and carbocycles has been designed and synthesized. The most potent novel bisphosphonates were shown to have lower minera... |
| Databáze: | OpenAIRE |
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