Effectivness of antral on oxidant-antioxidant homeostasis in patients with chronic pancreatitis
| Autor: | V. S. Smandych, I. V. Dudka, T. V. Dudka, O. S. Khukhlina, V. O. Pavliuk |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Exacerbation business.industry Stomach Glutathione medicine.disease_cause medicine.disease Gastroenterology Lipid peroxidation Pathogenesis chemistry.chemical_compound medicine.anatomical_structure Bloating chemistry Internal medicine medicine General Earth and Planetary Sciences Pancreatitis business Oxidative stress General Environmental Science |
| Zdroj: | Bukovinian Medical Herald. 24:140-148 |
| ISSN: | 2413-0737 1684-7903 |
| Popis: | Objective – to establish the effectiveness of Antral in the treatment of exacerbation phase of chronic pancreatitis (CP) based on a comprehensive assessment of the clinical course of CP and oxidative-antioxidant homeostasis.Material and methods. 52 patients with CP of mixed etiology in the moderate severity exacerbation phase were examined. To represent the effectiveness of treatment on a random basis, two representative groups of patients were formed. The average age of patients was (41.3±4.5) years. The design of the research included clinical, laboratory, biochemical blood tests, enzyme immunoassay, biochemical analysis of duodenal contents, coprogram, ultrasonography (USG) of the pancreas. Analysis of clinical, USG manifestations of CP, biochemical, laboratory indicators of the functional state of the pancreas was performed according to conventional methods, which were studied in the dynamics after 30 days of treatment.Results. Before treatment, a significant intensity of oxidative stress with an increase in the content of intermediate and final products of lipid peroxidation (1.6-1.7 times, p |
| Databáze: | OpenAIRE |
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