The combination of sorafenib and everolimus in patients with solid tumors: Results of a phase I study

Autor:	Christian Mattonet, H. Backes, Karin Toepelt, Thomas Elter, Matthias Scheffler, Carsten Kobe, Lucia Nogova, U. T. Hacker, Ildiko Katay, Nadia Harbeck, Peter Mallmann, Markus Dietlein, N. Muthen, Uwe Fuhr, Irini Papachristou, Kerstin Rhiem, Martin L. Sos, Roland Schnell, Juergen Wolf, M. Reiser
Rok vydání:	2011
Předmět:	Sorafenib Dual inhibition Cancer Research Everolimus Oncology business.industry Cancer research Medicine In patient business Discovery and development of mTOR inhibitors Phase i study medicine.drug
Zdroj:	Journal of Clinical Oncology. 29:e13613-e13613
ISSN:	1527-7755 0732-183X
Popis:	e13613 Background: The combination of the multi-kinase inhibitor sorafenib (S) and the mTOR inhibitor everolimus (E) may increase anti-tumor efficacy by dual inhibition of key nodules of signaling ...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::55a2089a97ae296a7e29db685379581e https://doi.org/10.1200/jco.2011.29.15_suppl.e13613 Zobrazit plný text záznamu