Production of Oligoalginate via Solution Plasma Process and Its Capability of Biological Growth Enhancement

Autor:	Minho Lee, Davoodbasha MubarakAli, Sang-Yul Lee, Jung-Wan Kim, Muhammed A.P. Manzoor
Rok vydání:	2021
Předmět:	Antioxidant Biocompatibility Chemistry Depolymerization medicine.medical_treatment HEK 293 cells Bioengineering General Medicine Free radical scavenger Applied Microbiology and Biotechnology Biochemistry In vitro Scientific method Toxicity medicine Food science Molecular Biology Biotechnology
Zdroj:	Applied Biochemistry and Biotechnology. 193:4097-4112
ISSN:	1559-0291 0273-2289
Popis:	The objective of the study was to depolymerize alginate into short-length oligoalginates, adopting the simple solution plasma process (SPP) technique, for successful use in free radical scavenging and growth promotion in cell culture and agricultural practices. Alginate at various concentrations was depolymerized to oligoalginates using SPP by discharging for various times. The depolymerization into oligoalginates was proved by DNS, TLC, FT-IR, and HPAEC analyses and caused decrease in viscosity. Oligoalginates derived from 0.5% alginate (100 mg∙mL−1) showed the highest antioxidant activities in vitro. The oligoalginates enhanced growth of the human embryonic kidney (HEK293) cells to significant levels in a concentration-dependent manner without any extent of toxicity. The oligoalginates also promoted growth of lettuce. Thus, SPP is a powerful technique to break down alginate into oligoalginates that can be utilized as a free radical scavenger and as a growth promoter of animal cells and agricultural plants.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::559fac7847a26afb794f156dba010e17 https://doi.org/10.1007/s12010-021-03640-7 Zobrazit plný text záznamu Full text from SpringerLink