Descemet Stripping Automated Endothelial Keratoplasty
| Autor: | Mark A. Terry, Asem A. Alqudah, Michael D. Straiko, Alex J. Bauer, P. James Sanchez |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
genetic structures business.industry medicine.medical_treatment Intraocular lens General Medicine Phacoemulsification Cataract surgery Fuchs' dystrophy medicine.disease Descemet stripping automated endothelial keratoplasty Endothelial cell density Endothelial stem cell 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Ophthalmology Descemet Stripping Endothelial Keratoplasty medicine 030212 general & internal medicine business |
| Zdroj: | Medicine. 99:e23139 |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | The purpose is to determine if the preoperative central endothelial cell density (ECD) in triple (phacoemulsification plus intraocular lens implantation plus DSAEK) and non-triple Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) procedures have a relationship with the 5-year postoperative ECD or percent Endothelial Cell Loss (ECL).Out of 986 consecutive DSAEK surgeries for Fuchs dystrophy, 241 eyes had 5-year ECD measurements available. Endothelial cell densities were then evaluated against preoperative ECDs to obtain measures of ECL. Triple and non-triple procedures were isolated and compared independently.One hundred eighty two eyes had undergone a triple procedure and 59 had not. The mean ECD at 5 years was 1560 ± 648 cells/mm for triples and 1483 ± 621 cells/mm for non-triples (P = .42). Endothelial Cell loss was 44.4% ± 21.7% and 44.4% ± 22.0%, respectively for eyes that underwent a triple or non-triple (P = .99). There was a moderate, but significant correlation between preoperative ECD and the ECD at 5 years after DSAEK for both triples (r = 0.39, P < .001), and non-triples (r = 0.32, P = .01), respectively.In Descemets stripping automated endothelial keratoplasty grafts, higher preoperative donor ECD was correlated with higher ECD at 5 years postoperatively but was unaffected by a concurrent cataract surgery in the triple procedure. |
| Databáze: | OpenAIRE |
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