Koronare Herzerkrankung bei Patienten mit obstruktiver Schlafapnoe
| Autor: | Bernd Sanner, Sturm A, Konermann M |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Coronary angiography
medicine.medical_specialty medicine.diagnostic_test business.industry Mortality rate Physical examination General Medicine Polysomnography Positive correlation medicine.disease Coronary heart disease nervous system diseases respiratory tract diseases stomatognathic system Internal medicine Angiography medicine Cardiology cardiovascular diseases business Hypopnea |
| Zdroj: | DMW - Deutsche Medizinische Wochenschrift. 121:931-935 |
| ISSN: | 1439-4413 0012-0472 |
| DOI: | 10.1055/s-2008-1043089 |
| Popis: | OBJECTIVE As patients with severe obstructive sleep apnoea (OSA) have increased cardiovascular morbidity and mortality rates, the prevalence of coronary heart disease (CHD) was investigated in patients with OSA proven by polysomnography (apnoea/hypopnea index > or = 10/h). PATIENTS AND METHODS In 440 patients (400 men, 40 women; mean age 55.3 [16-80] years) with OSA proven by polysomnography, the possible diagnosis of CHD was assessed by history, physical examination, ECG at rest and on exercise, one- and two-dimensional echocardiography and, where indicated, myocardial scintigraphy and coronary angiography. RESULTS CHD was demonstrated by angiography in 24.6% (men: 26.4%; women: 7.5%). Adding patients with CHD diagnosed noninvasively, but unconfirmed by angiography, positive correlation was found in 33.2% (men: 34.8%; women: 17.5%). CONCLUSION There was a high prevalence of CHD in patients with OSA. This underlines the importance of careful cardiac diagnosis in patients with OSA. |
| Databáze: | OpenAIRE |
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